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Going off the schedule

Yeah, I'm that good at content planning

Updated
3 min read
Going off the schedule

Business

An article about Avra

An elite accelerator for the world’s best startups and founders. Yeah, yeah...

Can you feel that startups are becoming an industry in themselves, with ‘value’ and ‘traction’ being the prime examples of Goodhart’s law - once people start valuing something*,* it’s usually great (wisdom of the crowds), but once everyone is jerking and showing off that same something (when everyone is raving about a stock, sell) - you know it’s slowly going to craps.

CB Insights’ insights. Such wow, much deep tech

Without further atalk:

  1. AI weather prediction, e.g. DeepMind’s NeuralGCM

  2. Ultra-deep drilling

  3. AI agent marketplaces; and hey look at this!

  4. Advanced nuclear propulsion

  5. Biocomputing. Turns out it’s not just brain organoids, but a whole (micro)-world of stuff!

  6. Brain manipulation tech

  7. Quantum-optimized portfolios

  8. Cellular & epigenetic reprogramming

  9. GPS-less navigation systems. Middle East, we’re looking at you.

EVs in Norway

Just look at this beauty of a chart:

Norway EVs

Health

10k in a pill

Guys from Aarhus University in Denmark (led by Dr Thomas Poulsen) had made a simple yet quite ingenious ‘exercise in a pill’:

Figure 1

  1. A precursor to lactate and beta-hydroxybutyrate which are elevated after exercise

  2. It’s orally available, easy to synthesize (lactate and BHB bonded)

  3. Novo Nordisk (the guys behind Ozempic epidemic) had already funded this research

  4. (2) and (3) lead me to believe it will enter the market quite soon, as Mmimetika Biosciences or under the NNordisk brand..

Diet and ASD

Dietary nutrients that potentially mitigate autism spectrum disorder and  dietary recommendations for children and pregnant women - Li - 2024 - Food  Frontiers - Wiley Online Library

TL;DR:

So it’s as usual: eat diverse foods, minimize gluten and casein, a sprinkle of polyphenols on top - et voila, you’re awesome!

Coffee and gut

The Gut Microbiome and its Effects on Human Health | Norgen Biotek Corp.

Inulin and migraines

  • Inulin decreased depression, stress and anxiety scores, as well as migraine clinical score

  • Didn’t change the QoL (quality of life) score, though…

Akkermansia vs Olanzapine

A newly identified protein from Akkermansia muciniphila stimulates GLP-1  secretion: Cell Metabolism

Among other virtues in weight management, (one being GLP-1 agonism, hehehe), Akkermansia muciniphilia will obviously help some for Olanzapine takers.

Ways to increase AM abundance are as usual:

  • Polyphenols

  • Inulin, FOS, GOS

  • Rhubarb and soy!

  • Regular exercise

  • Avoiding saturated fats, sugars, and excessive protein

  • Resistant/potato starch

Soo, just the usual “lead a healthy lifestyle, be happy and ye shall continue to do so”. If not, wait for the ‘10k in a pill’…


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