Some links of the past
PDCA vs OODA
PDCA
Plan-Do-Check-Act, or Deming wheel, Shewhart cycle, control circle
Designed to continuously improve a process or a system
Plan: objectives, requirements, constraints and methods are defined
Do: a pilot project/small-scale test
Check: performance check and adjustments
Act: permanent change and forward propagation
OODA
Developed by "40-second" John Boyde, an air pilot. I've written about OODA, and once more
The faster and better you iterate + the more you disrupt your opponents' loops ⇒ the better you end up
Observe-Orient-Decide-Act
Designed to be adaptable to unpredictable and volatile situations
SHAP analysis as a base for AI interpretation
Some quotes:
SHAP deconstructs a prediction into a sum of contributions from each of the model's input variables.1, [2]\
A machine learning model's prediction, f(x), can be represented as the sum of its computed SHAP values, plus a fixed base value, such that:
$$f(x) = base\;value + sum(SHAP\;values)$$
SHAP quantifies how important each input variable is to a model for making predictions
SHAP is a model-agnostic technique that can be applied to any machine learning algorithm
Waterfall plot
Bar plot
Beeswarm plot
Dependence plot
Perfect...pitch deck?
On average, founders need to pitch to about 40 investors over 12 weeks to close a round Shuaib (2024).
Traditional wisdom suggests some declines in investor activity during the summer months and around the Christmas holidays. While Holloway (2024) finds a lack of seasonality in VC funding based on the date of announcements
However, adding to the previous point, @VCBrags finds that a lot of VCs actually continue working during the summer, with no vacation
Investors look at your deck for ~ 2 minutes on average
In fact, the correlation between the number of investors you contact and the funds you raise is surprisingly weak (DocSend, 2024).
Psychedelics and PPI
No, that's Psychopharmacology Institute, not Proton Pump Inhibitors, ha!
Loved their intro to DMN:
Psychedelics disrupt DMN:
Consistent across various studies
Multiple psychedelics show effect
Intensity linked to experience
A nice overview on claustrum, a 5HT2Ar-rich zone that, based on different hypotheses, either integrates sensory input into a singular experiential flow (basis of qualia?) or switches between DMN and CEN (Central Executive Network).
An overview
Nicely disrupted...
So, in the end (I've tried so hard to write this post, but in the end it doesn't even matter):
Disruption of claustrum activity by psychedelics may contribute to synaesthetic experiences, too
It can also serve (wild non-neuro-broscience guess) as one of the inductors to neuroplasticity induction by 5HT2Ar activation, perhaps? E.g. "(the usual experiential flow is disrupted + excitability/stress are on the rise) ⇒ need to adapt to changing circumstances"
More links
reveal.js
A nice system for doing decks:
Welcome to Teleogenic❣️
Other places I cross-post (not always) to: